Tramadol is an opioid agonist that may be used to treat moderate to moderately severe chronic pain in adults, when other pain treatments such as non-opioid pain medicines do not treat your pain well enough, or you cannot tolerate them. Overview: Tramadol is an opioid pain medicine used to treat severe pain. It works by changing how your brain feels and reacts to pain. People take it by mouth as a tablet, capsule, or liquid. Tramadol hydrochloride tablets are: A strong prescription pain medicine that contains an opioid (narcotic) that is used for the management pain in adults, when other pain treatments such as non-opioid pain medicines do not treat your pain well enough or you cannot tolerate them. NHS medicines information on dosage for tramadol, how to take it and what to do if you miss a dose or take too much. Tramadol is a prescription generic drug used to treat pain. Learn about side effects, drug interactions, dosages, warnings, and more. Tramadol is used to relieve moderate to moderately severe pain, including pain after surgery. It is also used to treat pain severe enough to require opioid treatment and when other pain medicines did not work well enough or cannot be tolerated. Learn about tramadol usage and dosing. Read the latest news and reviews about the drug as well as potential side effects and popular alternatives. Detailed Tramadol dosage information for adults and the elderly. Includes dosages for Pain and Chronic Pain; plus renal, liver and dialysis adjustments. No effects on fertility were observed for tramadol at oral dose levels up to 50 mg/kg in male rats and 75 mg/kg in female rats. These dosages are 1.2 and 1.8 times the maximum recommended human daily dose based on body surface area, respectively. What is tramadol, and what is it used for? Tramadol is a synthetic (man-made) pain reliever (analgesic). Researchers and doctors do not know the exact mechanism of action of tramadol, but it is similar to morphine.